All I can do is respond to what worked for me. All the above applies to Renix stuff it seems, except for John's post above. With a stroker, with a 99+ intake manifold, and with a 62mm throttle body to match the manifold, all was well. Picked up a Hesco 62mm throttle body spacer, installed it, and had tranny late shifting problems due to the bend the TV and accelerator cables had to make with the valve cover cable guide at it's stock location. When I raised the cable guide guide up 1" off the valve cover to match the height of the spacer, everything was super smooth after the ECU relearned. It quieted down the too quick throttle response, smoothed the shift points, and improved idle a lot. It's time for another dyno run at Hesco since I've done quite a few mods since the last run, and I expect to see some slight improvement. Particularly if the new 96 throttle body mounted MAP provides the same outputs to the ECU over the RPM range.
Getting back to the OP's question, the answer is no, a TB spacer will do nothing harmful or gainful for an NA Renix. Not much of anything else will either. :yes: